Myrtle was unable to shake a second half run, falling to Ripley, 63-48, on Friday.
After Tasha Graham tied the game with her jumper right before the half, the Lady Tigers opened the third quarter with a three-pointer by Shunquest Howell, and Ripley went ahead by as many as 10 before a timeout by Myrtle.
Baskets by Aspriona Gilbert and Jenna Jordan made it a six-point game, but Ripley responded with a 6-0 run to take a 12-point lead into the fourth quarter.